国家卫生健康委员会医药卫生科技发展研究中心课题(WKZX2024GQ0202);湖南省卫生健康科研课题重点项目(20257411┫。This work was supported by the Project of the Development Center for Medical Science & Technology National Health Commission ┣WKZX2024GQ0202);the Key Project of Health Research Program of Hunan Provincial Health Commission(20257411);China.开放获取(Open access):本文遵循知识共享许可协议,允许第三方用户按照署名-非商业性使用-禁止演绎4.0(CC BY-NC-ND 4.0┫的方式;在任何媒介以任何形式复制、传播本作品┣https://creativecommons.org/licenses/by-nc-nd/4.0/)