Maresin 1 alleviates neuroinflammation and cognitive decline in a mouse model of cecal ligation and puncture
“New research reveals that maresin 1 (MaR1), an anti-inflammatory lipid mediator, can reduce neuroinflammation and improve cognitive impairment caused by sepsis. Mice treated with MaR1 showed reduced levels of inflammatory cytokines and improved survival rates. The study also found that MaR1 promotes the alternative activation of microglia in the hippocampus, which is beneficial for cognitive function.”
中南大学学报(医学版)中南大学学报(医学版)2024年49卷第6期 页码:890-902
作者机构:
1.中南大学湘雅医院麻醉科,长沙 410008
2.中南大学湘雅医院心血管内科,长沙 410008
3.中南大学湘雅医院国家老年疾病临床医学研究中心,长沙 410008
作者简介:
LI Longyan, Email: lilongyan2016@csu.edu.cn, ORCID: 0000-0003-2482-8470
the National Natural Science Foundation(81601728;31500726);the Natural Science Foundation of Hunan Province(2021JJ41002);Open access: This is an open access article under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International(CC BY-NC-ND 4.0┫ (https://creativecommons.org/licenses/by-nc-nd/4.0/))
LI Longyan, XING Manyu, WANG Lu, ZHAO Yixia. Maresin 1 alleviates neuroinflammation and cognitive decline in a mouse model of cecal ligation and puncture[J]. Journal of Central South University. Medical Science, 2024, 49(6): 890-902.
LI Longyan, XING Manyu, WANG Lu, ZHAO Yixia. Maresin 1 alleviates neuroinflammation and cognitive decline in a mouse model of cecal ligation and puncture[J]. Journal of Central South University. Medical Science, 2024, 49(6): 890-902. DOI:,10.11817/j.issn.1672-7347.2024.240117