Mouse kidney transplantation model: Three novel methods
“Researchers have developed new techniques for mouse kidney transplantation, a crucial model for transplantation immunology research. The study compared three surgical models, including the abdominal suture technique for orthotopic kidney transplantation, the abdominal cuff technique, and the cervical cuff technique for ectopic kidney transplantation. The modified abdominal suture technique and abdominal cuff technique have their respective advantages in research applications, while the novel cervical cuff technique for ectopic kidney transplantation is relatively simple to prepare and causes less trauma to the mice, providing more options for studies involving xenotransplantation, secondary transplantation, and local lymphatic drainage.”
DAI Helong, Email: helong68888@csu.edu.cn, ORCID: 0000-0002-0696-3081
基金信息:
the National Natural Science Foundation of China(82070776);Open access: This is an open access article under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International(CC BY-NC-ND 4.0┫ (https://creativecommons.org/licenses/by-nc-nd/4.0/))
TANG Zhouqi, FENG Chen, LI Yaguang, LI Tengfang, ZHANG Hedong, ZENG Yingqi, PENG Longkai, XIE Xubiao, PENG Fenghua, DAI Helong. Mouse kidney transplantation model: Three novel methods[J]. Journal of Central South University. Medical Science, 2024, 49(2): 220-235.
TANG Zhouqi, FENG Chen, LI Yaguang, LI Tengfang, ZHANG Hedong, ZENG Yingqi, PENG Longkai, XIE Xubiao, PENG Fenghua, DAI Helong. Mouse kidney transplantation model: Three novel methods[J]. Journal of Central South University. Medical Science, 2024, 49(2): 220-235. DOI:10.11817/j.issn.1672-7347.2024.230599