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铁死亡相关基因作为皮肤黑色素瘤预后因素的多组学分析(英文)

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皮肤疾病研究专题 | 更新时间:2024-05-31
    • 铁死亡相关基因作为皮肤黑色素瘤预后因素的多组学分析(英文)

    • Multi-omics analysis for ferroptosis-related genes as prognostic factors in cutaneous melanoma

    • In the field of melanoma research, a team of experts has developed a prognostic model based on ferroptosis-related genes (FRGs), which could offer new insights into personalized treatment and therapeutic outcomes for melanoma patients. By analyzing genetic alterations and mRNA expression of FRGs in melanoma samples, the researchers identified 13 FRGs associated with overall survival prognosis. The model, validated with external datasets, also showed significant differences in immune cell infiltration and predicted responses to immunotherapy and drug sensitivity between high- and low-risk groups.
    • 中南大学学报(医学版) 中南大学学报(医学版)   2024年49卷第2期 页码:159-174
    • 作者机构:

      1.湖南省人民医院皮肤科,长沙 410002

      2.湖南省中医药研究院附属医院(湖南省中西医结合医院)皮肤科, 长沙 410006

      3.湖南第一师范学院计算机学院,长沙 410205

    • 作者简介:

      WU Meng, Email: wmyouxiang163@163.com, ORCID: 0009-0009-5424-8697

      WANG Zheng, Email: w8614@hotmail.com, ORCID: 0009-0001-6518-028X

      FENG Hao, Email: doctorfenghao@hunnu.edu.cn, ORCID: 0000-0002-6057-1097

    • 基金信息:
      the Natural Science Foundation of Hunan Province(2021JJ30399);the Key Project of Health Commission of Hunan Province(202104122479)
    • DOI:10.11817/j.issn.1672-7347.2024.230401    

      中图分类号:
    • 纸质出版日期: 2024-02-28

      收稿日期: 2023-09-19

  • 吴猛, 李可, 廖阳英, 李蓝, 肖潇, 陈勇健, 郭俊玮辰, 胡丰, 曲靖, 汪政, 冯浩. 铁死亡相关基因作为皮肤黑色素瘤预后因素的多组学分析[J]. 中南大学学报(医学版), 2024, 49(2): 159-174. DOI:10.11817/j.issn.1672-7347.2024.230401

    WU Meng, LI Ke, LIAO Yangying, LI Lan, XIAO Xiao, CHEN Yongjian, GUO Junweichen, HU Feng, QU Jing, WANG Zheng, FENG Hao. Multi-omics analysis for ferroptosis-related genes as prognostic factors in cutaneous melanoma[J]. Journal of Central South University. Medical Science, 2024, 49(2): 159-174. DOI:10.11817/j.issn.1672-7347. 2024.230401

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