Abstract：We report and analyze the clinical data of the fi rst case of severe pneumonia caused by infl uenza B
virus from swine. Th e patient, a 62 year-old male domestic pig breeder, was admitt ed to hospital
because of fever and muscle pain for 5 days, and anhelation for 3 days. One week before the onset
of disease, the patient kept close contact with pigs. CT scan of the chest showed diff use infi ltration
in both lungs. Infl uenza B virus antigen detection (colloidal gold method) was repeatedly positive.
These all confirmed influenza B virus infection. Poor appetite, weight loss, cough, poor spirit of
pigs, positive influenza B virus antigen test occurred in the pig, while the patient had no history
of exposure to influenza B-infected patients. It was likely that influenza B virus was transmitted from domestic pigs to the patient by droplets or close contact. Influenza B virus epidemics always
occur every five or six years a time, and patients and carriers are the main source of infection. After
searching the Pubmed, Web of science, Elsevier, Wanfang, and CNKI databases, it was found that
although there were many studies on influenza B virus infecting seals, ferret, domestic pigs, guinea
pigs, and other animals, there was no case report for animal-to-human infection. It is the first case
report of type B influenza virus transmission from domestic pigs to people in the world, which
provides a new direction for the research and prevention of influenza B virus.
刘婷，姜亚峰，欧阳若芸. 猪传人重症乙型流行性感冒并肺炎1例及文献复习[J]. 中南大学学报(医学版), 2018, 43(11): 1266-1271.
LIU Ting, JIANG Yafeng, OUYANG Ruoyun. Swine-spread severe influenza-associated pneumonia: A case report and literature review. Journal of Central South University(Medical Scienc, 2018, 43(11): 1266-1271.
