neurosurgical patients to provide the basis for the prevention of postoperative DVT.

Methods: A total of 141 patients underwent neurosurgery were enrolled.

Thrombelastography (TEG) test was performed before and at the end of surgery. According

to whether there was DVT formation after operation, the patients were divided into a

thrombosis group and a non-thrombosis group. T-test and rank sum test were used to

compare the general clinical characteristics of the 2 groups, such as age, gender,

intraoperative blood loss, D-dimer, intraoperative crystal input, colloid input, blood product transfusion, operation duration, length of postoperative hospitalization. The application of

chi-square test and rank-sum test were used to compared TEG main test indicators such as

R and K values between the 2 groups. Logistic regression was used to analyze the possible

risk factors for postoperative DVT in neurosurgical patients.

Results: There were significant differences in postoperative TEG index R, clotting factor

function, intraoperative blood loss, hypertension or not, length of postoperative hospital

stay, and postoperative absolute bed time (all P<0.05). Logistic regression analysis showed

hypercoagulability, more intraoperative blood loss and longer postoperative absolute bed

time were risk factors for DVT formation after craniotomy.

Conclusion: Hypercoagulability in postoperative TEG test of patients is an important risk

factor for the formation of postoperative DVT after neurosurgery, which can predict the

occurrence of postoperative DVT to some extent.