Abstract：The cholinergic anti-inflammatory pathway (CAP) is a neuro-immunomodulatory pathway,
in which acetylcholine (ACh) released by the interaction of vagal nerves with α7 nicotinic
acetylcholine receptor (α7nAChR), which prevents the synthesis and release of proinflammatory
cytokines and ultimately regulates the local or systemic inflammatory
response in a feedback manner. It has been shown that there are many possible effective
treatments for sepsis, including vagus nerve stimulation by physical therapy, drugs such as
acetylcholine receptor agonist and ultrasound therapy.
资双凤，李景辉，刘蕾，刘芙蓉. 胆碱能抗炎通路及其在脓毒症治疗中的作用[J]. 中南大学学报(医学版), 2020, 45(1): 68-73.
ZI Shuangfeng, LI Jinghui, LIU Lei, LIU Furong. Cholinergic anti-inflammatory pathway and its role in treatment of sepsis. Journal of Central South University(Medical Scienc, 2020, 45(1): 68-73.
